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Anti -Rab11A Rabbit pAb

价格: 在线咨询
货号:
KT012280
产品规格:
100 μL
Applications:
WB
Species:
H/M/R
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information


Description

Rab11A rabbit polyclonal antibody

Protein full name

Ras-related protein Rab-11A

Synonyms

Rab-11, Rab11a, Rab11

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Rab11A

Isotype

IgG

Purity

Affinity purification

Predicted MW.

24 kDa

Observed MW.

24 kDa

Uniprot ID

P62491, P62492, P62494



Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

brain, spleen




Background


Rab proteins are low-molecular-weight GTP-binding proteins that form the largest branch of the Ras super family of GTPases. Located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fusion reactions. Three membrane proteins, synaptosomal associated protein of 25 kDa (SNAP-25), synaptobrevin, and syntaxin, form the core of a ubiquitous membrane fusion machine that interacts with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and a-SNAP. Rab proteins, in coordination with the core fusion machinery and Munc-18, help to mediate vesicle docking and fusion. Rab11a and Rab11b are known markers for protein trafficking, sorting, and recycling in the endosomal pathway. The Rab11 proteins are enriched in recycling endosomes and the trans-Golgi network, where they regulate membrane recycling back to the plasma membrane.




Images


Picture 1.png

Western blot analysis of RAB11A  at dilution of 1: 500




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.
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