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Anti -p115-RhoGEF Rabbit pAb
价格：
在线咨询
货号：
KT012275
产品规格：
100 μL
Applications：
IHC/IF
Species：
H/M/R
购买数量：
产品详情
操作说明
注意事项
Product Information
|
Description |
p115-RhoGEF rabbit polyclonal antibody |
|
Protein full name |
Rho guanine nucleotide exchange factor 1 |
|
Synonyms |
Lbc's second cousin, Lymphoid blast crisis-like 2, Arhgef1, Lbcl2, Lsc, p115RhoGEF, GEF1, LBCL2LSC |
|
Immunogen |
Recombinant protein corresponding to Mouse p115-RhoGEF |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Cytoplasm, Membrane |
|
Uniprot ID |
Q92888, Q61210, Q9Z1I6 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
IHC/IF |
Human, Mouse, Rat |
1: 500-1: 4000 |
lymph node, spleen, thymus, thyroid gland |
Background
This protein seems to play a role in the regulation of RhoA GTPase by guanine nucleotide binding alpha-12 (GNA12) and alpha-13 (GNA13) subunits. Acts as GTPase-activating protein (GAP) for GNA12 and GNA13, and as guanine nucleotide exchange factor (GEF) for RhoA GTPase. Activated G alpha 13/GNA13 stimulates the RhoGEF activity through interaction with the RGS-like domain. This GEF activity is inhibited by binding to activated GNA12. Mediates angiotensin-2-induced RhoA activation.
Images
|
Immunohistochemistry of paraffin embedded human thyroid gland using Arhgef1 at dilution of 1:2000 (400x lens) |
|
Immunohistochemistry of paraffin embedded mouse lymph node using Arhgef1 (GB111024) at dilution of 1:2000 (400x lens) |
|
Immunohistochemistry of paraffin embedded mouse spleen using Arhgef1 (GB111024) at dilution of 1:2000 (400x lens) |
|
Immunohistochemistry of paraffin embedded mouse thymus using Arhgef1 (GB111024) at dilution of 1:2000 (400x lens) |
|
Immunohistochemistry of paraffin embedded rat lymph node using Arhgef1 (GB111024) at dilution of 1:2000 (400x lens) |
|
Immunohistochemistry of paraffin embedded rat spleen using Arhgef1 (GB111024) at dilution of 1:2000 (400x lens) |
|
Immunofluorescence of paraffin embedded human lymph node using Arhgef1 (GB111024) at dilution of 1:2000 (400x lens) |
|
Immunofluorescence of paraffin embedded human thyroid gland using Arhgef1 (GB111024) at dilution of 1:2000 (400x lens) |
|
Immunofluorescence of paraffin embedded mouse lymph node using Arhgef1 (GB111024) at dilution of 1:2000 (400x lens) |
|
Immunofluorescence of paraffin embedded rat spleen using Arhgef1 (GB111024) at dilution of 1:2000 (400x lens) |
|
|
Immunofluorescence of paraffin embedded rat thymus using Arhgef1 (GB111024) at dilution of 1:2000 (400x lens) |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室