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Anti -LAT Rabbit pAb
价格：
在线咨询
货号：
KT012279
产品规格：
100 μL
Applications：
IHC/IF
Species：
M/R,H/M/R,H/M/R
购买数量：
在线咨询
400-1016-218
产品详情
操作说明
注意事项
Product Information
|
Description |
LAT rabbit polyclonal antibody |
|
Protein full name |
Linker for activation of T-cells family member 1 |
|
Synonyms |
36 kDa phospho-tyrosine adapter protein, pp36, p36-38, Lat |
|
Immunogen |
Recombinant protein corresponding to Mouse LAT |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Cell membrane |
|
Predicted MW. |
26 kDa |
|
Observed MW. |
38 kDa |
|
Uniprot ID |
O54957, O70601 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Mouse, Rat |
1: 500-1: 1000 |
spleen, thymus, lymph |
|
IHC/IF |
Human, Mouse, Rat |
1: 500-1: 4000 |
colon, thymus |
Background
Linker for activation of T-cells family member 1 (LAT) is a single-pass type III membrane protein which is required for TCR (T-cell antigen receptor) and pre-TCR-mediated signaling, both in mature T-cells and during their development This protein is involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Functionally T cell receptor (TCR) activation results in tyrosine phosphorylation of LAT, leading to the direct interaction with several proteins, including PLC-gamma 1, Grb2 and Gads.
Images
|
|
Western blot analysis of Lat at dilution of 1: 500 |
|
Immunohistochemistry of paraffin embedded mouse thymus using Lat (GB111123) at dilution of 1: 2000 (400x lens) |
|
Immunohistochemistry of paraffin embedded rat thymus using Lat (GB111123) at dilution of 1: 2000 (400x lens) |
|
Immunofluorescence of paraffin embedded human colon using Lat (GB111123) at dilution of 1: 2100 (400x lens) |
|
Immunofluorescence of paraffin embedded mouse thymus using Lat (GB111123) at dilution of 1: 2100 (400x lens) |
|
|
Immunofluorescence of paraffin embedded rat colon using Lat (GB111123) at dilution of 1: 2100 (400x lens) |
|
|
Immunofluorescence of paraffin embedded rat thymus using Lat (GB111123) at dilution of 1: 2100 (400x lens) |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室