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Anti -Rab5 Rabbit pAb
价格：
在线咨询
货号：
KT012276
产品规格：
100 μL
Applications：
WB/IHC/IF
Species：
H/M/R,H,H
购买数量：
产品详情
操作说明
注意事项
Product Information
|
Description |
Rab5 rabbit polyclonal antibody |
|
Protein full name |
Ras-related protein Rab-5A |
|
Synonyms |
Rab5a, NnyRab5a, Ubiquitin-protein ligase D3 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Human Rab5 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Cytoplasm, Cell membrane |
|
Predicted MW. |
24 kDa |
|
Observed MW. |
24 kDa |
|
Uniprot ID |
P20339, Q9CQD1 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
brain, testis |
|
IHC/IF |
Human |
1: 500-1: 2000 |
lung, lung cancer |
Background
Rab5 is a 24 kDa GTP-binding protein that regulates the fusion of plasma membrane -derived clathrin-coated vesicles with early endosomes, and homotypic fusion among early endosomes1. Localized to the cytoplasmic side of the plasma membrane, clathrin -coated vesicles and early endosomes, Rab5 appears to regulate vesicle fusion through a cycle of GDP/GTP e xchange and GTP hydrolysis. The different guanine nucleotide binding states of Rab5 may affect its ability to associate or dissociate with membranes during endocytotic membrane traffic.
Images
|
|
Western blot analysis of RAB5A (GB111104) at dilution of 1: 500 |
|
|
Immunohistochemistry of paraffin embedded human lung cancer using RAB5A (GB111104) at dilution of 1: 1000 (400x lens) |
|
|
Immunohistochemistry of paraffin embedded human lung using RAB5A (GB111104) at dilution of 1: 1000 (400x lens) |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室