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Anti -ADAR1 Rabbit pAb

价格: 在线咨询
货号:
KT012090
产品规格:
100 μL
Applications:
WB
Species:
H
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information


Description

ADAR1 rabbit polyclonal antibody

Protein full name

Double-stranded RNA-specific adenosine deaminase

Synonyms

DRADA, RNA adenosine deaminase 1, Adar, Adar1, 136kDa double stranded RNA binding protein, AGS6, Adenosine deaminase acting on RNA 1 A, Interferon inducible protein 4, RNA adenosine deaminase 1

Immunogen

Recombinant protein corresponding to Mouse ADAR1

Isotype

IgG

Purity

Affinity purification

Predicted MW.

130 kDa

Observed MW.

110 kDa

Uniprot ID

P55265




Applications


Applications

Species

Dilution

Positive Sample

WB

Human

1: 500-1: 1000

293T, Jurkat, HepG2, HeLa, DU145




Background


ADAR1 is also named as ADAR1, DSRAD, G1P1, IFI4. It convert selected adenosine residues into inosine in substrate RNAs containing a relatively short dsRNA region. The human ADAR1 gene specifies two size forms of RNA-specific adenosine deaminase, an interferon (IFN) inducible ∼150 kDa protein and a constitutively expressed N-terminally truncated ∼110 kDa protein, encoded by transcripts with alternative exon 1 structures that initiate from different promoters. It has 5 isoforms produced by alternative promoter usage and alternative splicing. Defects in ADAR are a cause of dyschromatosis symmetrical hereditaria (DSH).ADAR1 can form respective homodimers, and this association is essential for its enzymatic activities.




Images

Picture 1.png

Western blot analysis of ADAR1 (GB111458) at dilution of 1: 500




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).


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