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产品详情
操作说明
注意事项
Product Information
|
Description |
PABP rabbit polyclonal antibody |
|
Protein full name |
Polyadenylate-binding protein 1 |
|
Synonyms |
PABP-1, Poly(A)-binding protein 1, Pabpc1, Pabp1 |
|
Immunogen |
Recombinant protein corresponding to Mouse PABP |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Nucleus, Cytoplasm |
|
Predicted MW. |
71 kDa |
|
Observed MW. |
71 kDa |
|
Uniprot ID |
P29341, Q9EPH8 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
liver, testis, brain |
|
IHC/IF |
Mouse, Rat |
1: 1000-1: 4000 |
testis |
Background
PABPC1 binds the poly(A) tail of mRNA. It may be involved in cytoplasmic regulatory processes of mRNA metabolism such as pre-mRNA splicing. Its function in translational initiation regulation can either be enhanced by PAIP1 or repressed by PAIP2. PABPC1 can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo. It may be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.
Images
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Western blot analysis of pabp1 (GB111164) at dilution of 1: 500 |
|
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Immunohistochemistry of paraffin embedded mouse testis using pabp1 (GB111164) at dilution of 1: 1200 (400x lens) |
|
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Immunohistochemistry of paraffin embedded rat testis using pabp1 (GB111164) at dilution of 1: 1200 (400x lens) |
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Immunofluorescence of paraffin embedded mouse testis using pabp1 (GB111164) at dilution of 1: 3913 (400x lens) |
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Immunofluorescence of paraffin embedded rat testis using pabp1 (GB111164) at dilution of 1: 3913 (400x lens) |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室