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产品详情
操作说明
注意事项
Product Information
|
Description |
YTHDF1 rabbit polyclonal antibody |
|
Protein full name |
YTH domain-containing family protein 1 |
|
Synonyms |
Dermatomyositis associated with cancer putative autoantigen 1 homolog, DACA-1 homolog, Ythdf1 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse YTHDF1 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Cytoplasm |
|
Uniprot ID |
P59326 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
IHC/IF |
Mouse, Rat |
1: 500-1: 1000 |
brain |
Background
YTHDF1, also named as YTH domain-containing family protein 1 or C20orf21. YTHDF1 specifically recognizes and binds N6-methyladenosine (m6A)-containing mRNAs, and promotes mRNA translation efficiency. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability. YTHDF1 acts as a regulator of mRNA translation efficiency: promotes ribosome loading to m6A-containing mRNAs and interacts with translation initiation factors eIF3 (EIF3A or EIF3B) to facilitate translation initiation.
Images
|
|
Immunohistochemistry of paraffin embedded mouse brain using YTHDF1 (GB111390) at dilution of 1:500 (400x lens) |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室