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Anti -SAM68 Rabbit pAb

价格: 在线咨询
货号:
KT012068
产品规格:
100 μL
Applications:
WB/IHC/IF
Species:
HMR/HMR
购买数量:
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产品详情 操作说明 注意事项

Product Information


Description

SAM68 rabbit polyclonal antibody

Protein full name

KH domain-containing, RNA-binding, signal transduction-associated protein 1

Synonyms

GAP-associated tyrosine phosphoprotein p62, Src-associated in mitosis 68 kDa protein, Sam68, p21 Ras GTPase-activating protein-associated p62, p68, Khdrbs1

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse SAM68

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm, Nucleus

Predicted MW.

48 kDa

Observed MW.

68 kDa

Uniprot ID

Q07666, Q60749, Q91V33




Applications


Applications

Species

Dilution

Positive Sample

WB

Human, Mouse, Rat

1: 500-1: 1000

lung, brain

IHC/IF

Human, Mouse, Rat

1: 500-1: 3000

brain, breast cancer, lung, lung cancer, ovarian cancer, ovary, skeletal muscle, skin




Background


SAM68, also named as KHDRBS1, p62and p68, belongs to the KHDRBS family. It is recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once phosphorylated, SAM68 functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain-containing proteins. It represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP.




Images


Western blot analysis of SAM68 (GB111224) at dilution of 1: 500

Immunohistochemistry of paraffin embedded human lung cancer using SAM68 (GB111224) at dilution of 1: 1500 (400x lens)

Immunohistochemistry of paraffin embedded human ovarian cancer using SAM68 (GB111224) at dilution of 1: 1500 (400x lens)

Immunohistochemistry of paraffin embedded mouse brain using SAM68 (GB111224) at dilution of 1: 1500 (400x lens)

Immunohistochemistry of paraffin embedded mouse lung using SAM68 (GB111224) at dilution of 1: 1500 (400x lens)

Immunohistochemistry of paraffin embedded mouse skeletal muscle using SAM68 (GB111224) at dilution of 1: 1500 (400x lens)

Immunohistochemistry of paraffin embedded rat brain using SAM68 (GB111224) at dilution of 1: 1500 (400x lens)

Immunohistochemistry of paraffin embedded rat ovary using SAM68 (GB111224) at dilution of 1: 1500 (400x lens)

Immunohistochemistry of paraffin embedded rat skeletal muscle using SAM68 (GB111224) at dilution of 1: 1500 (400x lens)

Immunohistochemistry of paraffin embedded rat skin using SAM68 (GB111224) at dilution of 1: 1500 (400x lens)

Immunofluorescence of paraffin embedded human breast cancer using SAM68 (GB111224) at dilution of 1: 1500 (400x lens)

Immunofluorescence of paraffin embedded mouse brain using SAM68 (GB111224) at dilution of 1: 1500 (400x lens)


Immunofluorescence of paraffin embedded mouse skin using SAM68 (GB111224) at dilution of 1: 1500 (400x lens)

Immunofluorescence of paraffin embedded rat brain using SAM68 (GB111224) at dilution of 1: 1500 (400x lens)




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).


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