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Product Information
Description |
SAM68 rabbit polyclonal antibody |
Protein full name |
KH domain-containing, RNA-binding, signal transduction-associated protein 1 |
Synonyms |
GAP-associated tyrosine phosphoprotein p62, Src-associated in mitosis 68 kDa protein, Sam68, p21 Ras GTPase-activating protein-associated p62, p68, Khdrbs1 |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse SAM68 |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
Cytoplasm, Nucleus |
Predicted MW. |
48 kDa |
Observed MW. |
68 kDa |
Uniprot ID |
Q07666, Q60749, Q91V33 |
Applications
Applications |
Species |
Dilution |
Positive Sample |
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
lung, brain |
IHC/IF |
Human, Mouse, Rat |
1: 500-1: 3000 |
brain, breast cancer, lung, lung cancer, ovarian cancer, ovary, skeletal muscle, skin |
Background
SAM68, also named as KHDRBS1, p62and p68, belongs to the KHDRBS family. It is recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once phosphorylated, SAM68 functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain-containing proteins. It represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP.
Images
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Western blot analysis of SAM68 (GB111224) at dilution of 1: 500 |
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Immunohistochemistry of paraffin embedded human lung cancer using SAM68 (GB111224) at dilution of 1: 1500 (400x lens) |
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Immunohistochemistry of paraffin embedded human ovarian cancer using SAM68 (GB111224) at dilution of 1: 1500 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse brain using SAM68 (GB111224) at dilution of 1: 1500 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse lung using SAM68 (GB111224) at dilution of 1: 1500 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse skeletal muscle using SAM68 (GB111224) at dilution of 1: 1500 (400x lens) |
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Immunohistochemistry of paraffin embedded rat brain using SAM68 (GB111224) at dilution of 1: 1500 (400x lens) |
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Immunohistochemistry of paraffin embedded rat ovary using SAM68 (GB111224) at dilution of 1: 1500 (400x lens) |
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Immunohistochemistry of paraffin embedded rat skeletal muscle using SAM68 (GB111224) at dilution of 1: 1500 (400x lens) |
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Immunohistochemistry of paraffin embedded rat skin using SAM68 (GB111224) at dilution of 1: 1500 (400x lens) |
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Immunofluorescence of paraffin embedded human breast cancer using SAM68 (GB111224) at dilution of 1: 1500 (400x lens) |
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Immunofluorescence of paraffin embedded mouse brain using SAM68 (GB111224) at dilution of 1: 1500 (400x lens) |
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Immunofluorescence of paraffin embedded mouse skin using SAM68 (GB111224) at dilution of 1: 1500 (400x lens) |
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Immunofluorescence of paraffin embedded rat brain using SAM68 (GB111224) at dilution of 1: 1500 (400x lens) |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).
合肥万物生物科技有限公司
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