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Product Information
Description |
EFTUD2 rabbit polyclonal antibody |
Protein full name |
116 kDa U5 small nuclear ribonucleoprotein component |
Synonyms |
Snrp116, Elongation factor Tu GTP-binding domain-containing protein 2, U5-116 kDa, U5 snRNP-specific protein,116 kDa, EFTUD2 |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse EFTUD2 |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
Nucleus |
Predicted MW. |
109 kDa |
Observed MW. |
130 kDa |
Uniprot ID |
Q15029, O08810 |
Applications
Applications |
Species |
Dilution |
Positive Sample |
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
brain, liver |
IHC/IF |
Human, Mouse, Rat |
1: 500-1: 3000 |
brain, colon cancer, liver, lung, lung cancer, ovarian cancer, ovary, testis |
Background
EFTUD2 encodes the 116 kDa U5 small nuclear ribonecleoprotein (snRNP) component, also named SNU114, it has GTP binding activity and is required for pre-mRNA splicing. Evolutionarily conserved human snRNP protein (U5-116kDa) is homologous to the ribosomal elongation factor EF-2 (ribosomal translocase). Defects in EFTUD2 are the cause of mandibulofacial dysostosis with microcephaly (MFDM).
Images
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Western blot analysis of EFTUD2 (GB111188) at dilution of 1: 500 |
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Immunohistochemistry of paraffin embedded human colon cancer using EFTUD2 (GB111188) at dilution of 1: 2400 (400x lens) |
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Immunohistochemistry of paraffin embedded human lung cancer using EFTUD2 (GB111188) at dilution of 1: 2400 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse brain using EFTUD2 (GB111188) at dilution of 1: 2400 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse lung using EFTUD2 (GB111188) at dilution of 1: 2400 (400x lens) |
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Immunohistochemistry of paraffin embedded rat brain using EFTUD2 (GB111188) at dilution of 1: 2400 (400x lens) |
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Immunohistochemistry of paraffin embedded rat lung using EFTUD2 (GB111188) at dilution of 1: 2400 (400x lens) |
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Immunohistochemistry of paraffin embedded rat ovary using EFTUD2 (GB111188) at dilution of 1: 2400 (400x lens) |
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Immunofluorescence of paraffin embedded human ovarian cancer using EFTUD2 (GB111188) at dilution of 1: 2400 (400x lens) |
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Immunofluorescence of paraffin embedded mouse liver using EFTUD2 (GB111188) at dilution of 1: 2400 (400x lens) |
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Immunofluorescence of paraffin embedded mouse lung using EFTUD2 (GB111188) at dilution of 1: 2400 (400x lens) |
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Immunofluorescence of paraffin embedded rat brain using EFTUD2 (GB111188) at dilution of 1: 2400 (400x lens) |
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Immunofluorescence of paraffin embedded rat testis using EFTUD2 (GB111188) at dilution of 1: 2400 (400x lens) |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025)
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