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产品详情
操作说明
注意事项
Product Information
|
Description |
Myoglobin rabbit polyclonal antibody |
|
Protein full name |
Myoglobin |
|
Synonyms |
Mb, MB, PVALB, myoglobgin, myoglobin, Myoglobin |
|
Immunogen |
Recombinant protein corresponding to Human Myoglobin |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
17 kDa |
|
Observed MW. |
17 kDa |
|
Uniprot ID |
P04247, Q9QZ76 |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Mouse, Rat |
1: 500-1: 1000 |
heart, skeletal muscle |
Background
Myoglobin is a small heme containing protein responsible for the oxygen deposition in muscle tissues. Only one form of myoglobin is expressed in cardiac and skeletal muscles. Myoglobin is known as a marker of myocardial damage and it has been used for more than three decades. Nowadays it still is very commonly used in clinical practice as an early marker of AMI. It appears in patient's blood 1 to 3 hours after onset of the symptoms, reaching peak level within 8 to 12 hours. Myoglobin is not so cardiac specific as cTnI or cTnT. Because of high myoglobin concentration in skeletal muscle tissue, even minor skeletal muscle injury results in the significant increase of myoglobin concentration in blood. Thus myoglobin is used together with cTnI or cTnT in clinical practise for better specificity in AMI diagnosis.
Images
|
|
Western blot analysis of Myoglobin (GB111170) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室