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Product Information
Description |
Heme Oxygenase 1 rabbit polyclonal antibody |
Protein full name |
Heme oxygenase 1 |
Synonyms |
HMOX1, HMOX1D, HO-1, HSP32, bK286B10, heme oxygenase 1 |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse HMOX1 |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
Microsome, Endoplasmic reticulum membrane |
Uniprot ID |
P14901 |
Applications
Applications |
Species |
Dilution |
Positive Sample |
IHC/IF |
Mouse, Rat |
1: 200-1: 2000 |
lung, spleen |
Background
Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis.
Images
Immunohistochemistry of paraffin embedded mouse lung using HMOX1 (GB11104) at dilution of 1:200 (400x lens) | |
Immunohistochemistry of paraffin embedded mouse spleen using HMOX1 (GB11104) at dilution of 1:200 (400x lens) | |
Immunohistochemistry of paraffin embedded rat lung using HMOX1 (GB11104) at dilution of 1:200 (400x lens) | |
Immunohistochemistry of paraffin embedded rat spleen using HMOX1 (GB11104) at dilution of 1:200 (400x lens) | |
Immunofluorescence of paraffin embedded mouse spleen using HMOX1 (GB11104) at dilution of 1:2000 (400x lens) | |
|
Immunofluorescence of paraffin embedded rat spleen using HMOX1 (GB11104) at dilution of 1:2000 (400x lens) |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).
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