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Anti -Cyclin E1 Rabbit pAb

价格: 在线咨询
货号:
KT011869
产品规格:
100 μL
Applications:
WB
Species:
H,M,R
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information


Description

Cyclin E1 rabbit polyclonal

Protein full name

G1/S-specific cyclin-E1

Synonyms

CCNE1, CCNE, pcyclin E1, Cyclin E1

Immunogen

KLH conjugated Synthetic peptide

corresponding to Human Cyclin E1

Isotype

IgG

Purity

Affinity purification

Predicted MW.

47 kDa

Observed MW.

47 kDa

Uniprot ID

P24864, Q61457, P39949




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 900

testis, colon, placenta




Background


Cyclin E1 (CCNE1) is a member of the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. CCNE1, an essential cyclin activating Cdk2, regulates the G1-S phase transition of the mammalian cell division cycle. Its timing expression plays a direct role in the initiation of DNA replication , the control of histone biosynthesis, and the centrosome cycle. CCNE1 is associated with disease progression in various malignancies and is associated clinically with poor prognosis.




Images


图片 1.png

Western blot analysis of Cyclin E1 

at dilution of 1: 500

Lane 1: HeLa cell lysate

Lane 2: MCF7 cell lysate

Lane 3: K562 cell lysate

Lane 4: Mouse testis tissue lysate

Lane 5: Mouse colon tissue lysate

Lane 6: Mouse placenta tissue lysate

Lane 7: Rat testis tissue lysate

Lane 8: Rat colon tissue lysate

Lane 9: Rat placenta tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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