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产品详情
操作说明
注意事项
Product Information
|
Description |
Cyclin D1 rabbit polyclonal antibody |
|
Protein full name |
G1/S-specific cyclin-D1 |
|
Synonyms |
CCND1, BCL1, D11S287E, PRAD1, U21B31, cyclin D1 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse Cyclin D1 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
33 kDa |
|
Observed MW. |
33 kDa |
|
Uniprot ID |
P25322 |
Applications
|
applications |
species |
dilution |
Positive tissue |
|
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
lung, kidney, brain |
Background
The protein belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDKs (Cyclin-dependent kinase). Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb.
Images
|
|
Western blot analysis of Cyclin D1 (GB11079) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室