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产品详情
操作说明
注意事项
Product Information
|
Description |
Cyclin D1 rabbit polyclonal antibody |
|
Protein full name |
G1/S-specific cyclin-D1 |
|
Synonyms |
Ccnd1, Cyl-1, B-cell lymphoma 1 protein, BCL-1, Parathyroid adenomatosis 1, PRAD1, BCL1 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse Cyclin D1 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
33 kDa |
|
Observed MW. |
33 kDa |
|
Uniprot ID |
P24385, P25322, P39948 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
MCF-7, A431, SH-SY5Y, THP-1, L929, RAW 264.7, C6, PC-12 |
Background
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb.
Images
|
Western blot analysis of cyclinD1 (GB111935) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室