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产品详情
操作说明
注意事项
Product Information
|
Description |
HEC1 rabbit polyclonal antibody |
|
Protein full name |
Kinetochore protein NDC80 homolog |
|
Synonyms |
Kinetochore protein Hec1, Hec1, Kntc2, Kinetochore-associated protein 2, Ndc80 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse HEC1 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
74 kDa |
|
Observed MW. |
74 kDa |
|
Uniprot ID |
Q9D0F1 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Mouse, Rat |
1: 500-1: 1000 |
testis, spleen |
Background
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules. Plays a role in chromosome congression and is essential for the end-on attachment of the kinetochores to spindle microtubules.
Images
|
|
Western blot analysis of NDC80 (GB111227) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室