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产品详情
操作说明
注意事项
Product Information
|
Description |
S6K1 rabbit polyclonal antibody |
|
Protein full name |
Ribosomal protein S6 kinase beta-1 |
|
Synonyms |
S6K-beta-1, S6K1, P70S6K1, S6K, Ribosomal protein S6 kinase I, p70 S6 kinase alpha, Rps6kb1, 70 kDa ribosomal protein S6 kinase 1 |
|
Immunogen |
Recombinant protein corresponding to Mouse S6K1 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
59 kDa |
|
Observed MW. |
70 kDa |
|
Uniprot ID |
P23443, Q8BSK8, P67999 |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
brain, testis |
Background
This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases that acts downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression. Regulates protein synthesis through phosphorylation of EIF4B, RPS6 and EEF2K, and contributes to cell survival by repressing the pro-apoptotic function of BAD. Under conditions of nutrient depletion, the inactive form associates with the EIF3 translation initiation complex.
Images
|
|
Western blot analysis of P70S6K1 (GB111133) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室