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Anti -CD63 Rabbit pAb

价格: 在线咨询
货号:
DRF101875
产品规格:
100 μL
Applications:
Species:
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information


Description

CD63 rabbit polyclonal

Protein full name

CD63 antigen

Synonyms

CD63, LAMP-3, ME491, MLA1, OMA81H, TSPAN30, CD63 molecule, Lysosomal associated membrane protein 3, LAMP3, CD63 antigen, NGA, Tetraspanin-30

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse CD63

Isotype

IgG

Purity

Affinity purification

Subcellular location

Secreted, Cell membrane, Cytoplasm

Uniprot ID

P41731, P28648




Applications


applications

species

dilution

positive tissue

IHC

Mouse, Rat

1: 500-1: 3000

lung, liver

IF

Mouse, Rat

1: 500-1: 1500

lung, brain




Background


CD63 antigen is a protein is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth, and motility. CD63 is a cell surface glycoprotein that is known to complex with integrins.CD63 is mainly associated with membranes of intracellular vesicles, although cell surface expression may be induced.  It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak Syndrome. Also this gene CD63 has been associated with tumor progression.




Images



image.png

Immunohistochemistry analysis of paraffin-embedded mouse lung using

CD63 (GB11620) at dilution of 1: 750


image.png

Immunohistochemistry analysis of paraffin-embedded rat lung using

CD63 (GB11620) at dilution of 1: 750


image.png

Immunohistochemistry analysis of paraffin-embedded mouse liver using

CD63 (GB11620) at dilution of 1: 750


Immunofluorescent analysis of paraformaldehyde-fixed rat lung using

CD63 (GB11620) at dilution of 1: 1500



Immunofluorescent analysis of paraformaldehyde-fixed rat brain using

CD63 (GB11620) at dilution of 1: 1500




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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