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产品详情
操作说明
注意事项
Product Information
|
Description |
CD11c rabbit polyclonal |
|
Protein full name |
Integrin alpha-X |
|
Synonyms |
ITGAX, CD11C, SLEB6, integrin subunit alpha X |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse CD11c |
|
Isotype |
IgG |
|
Predicted MW. |
129 KDa |
|
Observed MW. |
150 KDa |
|
Purity |
Affinity purification |
|
Subcellular location |
|
|
Uniprot ID |
Applications
|
applications |
species |
dilution |
Positive tissue |
|
WB |
Mouse |
1: 500-1: 1000 |
thymus, spleen, inflammatory lung |
|
IHC |
Human, Mouse, Rat |
1: 200-1: 400 |
tonsil, inflammatory lung, lung, splenitis |
|
IF |
Human, Mouse, Rat |
1: 200-1: 400 |
pneumonia, spleen |
Background
This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene.
Images
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Western blot analysis of CD11c(GB11059) at dilution of 1:1000 Lane 1: Raw264.7 cell lysate Lane 2: Mouse spleen tissue lysate Lane 3: Mouse inflammatory lung tissue lysate Lane 4: Mouse thymus tissue lysate |
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Immunohistochemistry analysis of paraffin-embedded human tonsil using CD11c(GB11059) at dilution of 1: 400 |
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Immunohistochemistry analysis of paraffin-embedded mouse inflammatory lung using CD11c(GB11059) at dilution of 1: 400 |
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Immunohistochemistry analysis of paraffin-embedded mouse lung using CD11c(GB11059) at dilution of 1: 400 |
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Immunohistochemistry analysis of paraffin-embedded mouse splenitis using CD11c(GB11059) at dilution of 1: 400 |
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Immunofluorescent analysis of paraformaldehyde-fixed rat inflammatory lung using CD11c(GB11059) at dilution of 1: 400 |
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Immunofluorescent analysis of paraformaldehyde-fixed rat spleen using CD11c(GB11059) at dilution of 1: 400 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室