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Product Information
Description |
CD31 rabbit polyclonal |
Protein full name |
Platelet endothelial cell adhesion molecule |
Synonyms |
CD31 Antigen, EndoCAM, PECAM-1, GPIIA, PECA1 |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse CD31 |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
|
Predicted MW. |
81 kDa |
Observed MW. |
120 kDa |
Uniprot ID |
Applications
applications |
species |
dilution |
Positive tissue |
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
lung, thymus |
IHC |
Human, Mouse, Rat |
1: 600-1: 1200 |
liver cancer |
IF |
Human, Mouse, Rat |
1: 200-1: 1000 |
gastric cancer, liver cancer, lung, placenta |
Background
Platelet endothelial cell adhesion molecule (PECAM-1) also known as cluster of differentiation 31 (CD31) is a protein that in humans is encoded by the PECAM1 gene found on chromosome 17. PECAM-1 plays a key role in removing aged neutrophils from the body. PECAM-1 is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte transmigration, angiogenesis, and integrin activation.
Images
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Western blot analysis of CD31 (GB11063-2) at dilution of 1: 1000
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Immunohistochemistry analysis of paraffin-embedded human liver cancer using CD31 (GB11063-2) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded human liver cancer using CD31 (GB11063-2) at dilution of 1: 2000 |
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Immunofluorescent analysis of paraformaldehyde-fixed human gastric cancer using CD31 (GB11063-2) at dilution of 1: 2000 |
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Immunofluorescent analysis of paraformaldehyde-fixed human liver cancer using CD31 (GB11063-2) at dilution of 1: 2000 |
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Immunofluorescent analysis of paraformaldehyde-fixed rat lung using CD31 (GB11063-2) at dilution of 1: 2000
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Immunofluorescent analysis of paraformaldehyde-fixed rat placenta using CD31 (GB11063-2) at dilution of 1: 2000
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Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
Publications:
|
Title |
Journal |
Pubmed ID |
Application |
1 |
IL-21 Stimulates the expression and activation of cell cycle regulators and promotes cell proliferation in EBV-positive diffuse large B cell lymphoma. |
Scientific Reports |
32704112 |
IHC |
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