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产品详情
操作说明
注意事项
Product Information
|
Description |
CD45 rabbit polyclonal |
|
Protein full name |
Receptor-type tyrosine-protein phosphatase C |
|
Synonyms |
PTPRC, B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200, protein tyrosine phosphatase, receptor type C |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse CD45 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
|
|
Uniprot ID |
Applications
|
applications |
species |
dilution |
Positive tissue |
|
IHC |
Mouse, Rat |
1: 1000-1: 3000 |
spleen,lung,liver |
|
IF |
Mouse, Rat |
1: 2000-1: 4000 |
lymph node inflammation |
Background
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity.
Images
|
|
Immunohistochemistry analysis of paraffin-embedded mouse liver using CD45(GB11066) at dilution of 1: 1500 |
|
|
Immunohistochemistry analysis of paraffin-embedded mouse spleen using CD45(GB11066) at dilution of 1: 1500 |
|
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Immunohistochemistry analysis of paraffin-embedded mouse lung using CD45(GB11066) at dilution of 1: 1500 |
|
|
Immunofluorescent analysis of paraformaldehyde-fixed mouse lymph node inflammation using CD31 (GB11063-2) at dilution of 1: 800 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室