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产品详情
操作说明
注意事项
Product Information
|
Description |
CD105 rabbit polyclonal |
|
Protein full name |
Endoglin |
|
Synonyms |
Cell surface MJ7/18 antigen, CD105, Eng, Edg, FLJ41744, HHT1, ORW, ORW1 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Human CD105 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
|
|
Uniprot ID |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
IHC |
Human |
1: 500-1: 1000 |
colon carcinoma, liver cancer, |
|
IF |
Human |
1: 500-1: 1000 |
liver cancer, ovarian cancer |
Background
Endoglin (ENG, CD105) is a homodimeric cell membrane glycoprotein of 180 kDa, composed of disulphide-linked subunits of 95 kDa. Endoglin is a proliferation-associated and hypoxia-inducible protein mainly expressed on vascular endothelial cells. It acts as an accessory receptor for transforming growth factor beta (TFG-β) and is involved in vascular development and remodelling. The important role of Endoglin in angiogenesis and in tumor progression makes it an ideal target for antiangiogenic therapy and a good marker for tumor prognosis.
Images
|
|
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma using CD105 (GB113377) at dilution of 1: 1000 |
|
|
Immunohistochemistry analysis of paraffin-embedded human liver cancer using CD105 (GB113377) at dilution of 1: 1000 |
|
|
Immunohistochemistry analysis of paraffin-embedded human ovarian cancer using CD105 (GB113377) at dilution of 1: 1000 |
|
|
Immunofluorescent analysis of paraformaldehyde-fixed humanliver cancer using CD105 (GB113377) at dilution of 1: 1000 |
|
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Immunofluorescent analysis of paraformaldehyde-fixed human ovarian cancer using CD105 (GB113377) at dilution of 1: 1000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室