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Product Information
Description |
CD62p rabbit polyclonal |
Protein full name |
P-selectin |
Synonyms |
CD62 antigen-like family member P, Granule membrane protein 140, GMP-140, LECAM3, Platelet activation dependent granule-external membrane protein, Leukocyte-endothelial cell adhesion molecule 3, PADGEM, CD62P, Grmp, Selp |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse CD62p |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
|
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
IHC |
Rat |
1: 500-1: 1000 |
liver, kidney |
Background
This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented.
Images
|
Immunohistochemistry analysis of paraffin-embedded rat liver using CD62p (GB112166) at dilution of 1: 1000 |
Immunohistochemistry analysis of paraffin-embedded rat kidney using CD62p (GB112166) at dilution of 1: 1000 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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