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产品详情
操作说明
注意事项
Product Information
|
Description |
Flt3 rabbit polyclonal |
|
Protein full name |
Receptor-type tyrosine-protein kinase FLT3 |
|
Synonyms |
FL cytokine receptor, Fetal liver kinase 2, FLK-2, Fms-like tyrosine kinase 3, FLT-3, Tyrosine-protein kinase receptor flk-2, CD135, Flt3, Flk-2, Flt-3 |
|
Immunogen |
Recombinant protein corresponding to Mouse Flt3 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Cytoplasm |
|
Predicted MW. |
113 kDa |
|
Observed MW. |
130/160 kDa |
|
Uniprot ID |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
liver, thymus, spleen |
|
IHC |
Mouse, Rat |
1: 1000-1: 4000 |
immune spleen, brain |
|
IF |
Mouse, Rat |
1: 1000-1: 3000 |
brain, placenta, cartilage |
Background
FLT3 (also known as CD135 or FLK2) is a tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. FLT3 was originally identified by its expression in hematopoietic stem/progenitor cells . It is important for the normal development of hematopoietic stem/progenitor cells. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.
Images
|
|
Western blot analysis of Flt3 (GB111358) |
|
Immunohistochemistry analysis of paraffin-embedded mouse immune spleen using Flt3 (GB111358) at dilution of 1: 2000 |
|
Immunohistochemistry analysis of paraffin-embedded mouse brain using Flt3 (GB111358) at dilution of 1: 2000 |
|
Immunohistochemistry analysis of paraffin-embedded rat brain using Flt3 (GB111358) at dilution of 1: 2000 |
|
Immunofluorescent analysis of paraformaldehyde-fixed mouse brain using Flt3 (GB111358) at dilution of 1: 2000 |
|
Immunofluorescent analysis of paraformaldehyde-fixed mouse placenta using Flt3 (GB111358) at dilution of 1: 2000 |
|
Immunofluorescent analysis of paraformaldehyde-fixed rat cartilage using Flt3 (GB111358) at dilution of 1: 2000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室