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Product Information
Description |
CD10 rabbit polyclonal |
Protein full name |
Neprilysin |
Synonyms |
Atriopeptidase, Enkephalinase, SFE, CD10, Neutral endopeptidase 24.11, NEP, Neutral endopeptidase, Skin fibroblast elastase, Mme |
Immunogen |
Recombinant protein corresponding to Mouse CD10 |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
86 kDa |
Observed MW. |
100 kDa |
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Mouse, Rat |
1: 500-1: 1000 |
kidney, prostate |
Background
This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin.
Images
Western blot analysis of CD10 (GB111120) at dilution of 1: 1000 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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