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Anti -Raptor Rabbit pAb

价格: 在线咨询
货号:
KT012206
产品规格:
100 μL
Applications:
WB
Species:
HM
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information


Description

Raptor rabbit polyclonal antibody

Protein full name

Regulatory-associated protein of mTOR

Synonyms

RPTOR, KOG1, Mip1, regulatory associated protein of MTOR complex 1, KIAA1303, P150 target of rapamycin (TOR)-scaffold protein

Immunogen

Recombinant protein corresponding to Mouse Raptor

Isotype

IgG

Purity

Affinity purification

Predicted MW.

73 kDa

Observed MW.

73 kDa

Uniprot ID

Q8K4Q0, Q8N122




Applications


Applications

Species

Dilution

Positive Sample

WB

Human, Mouse

1: 500-1: 1000

lung, colon, brain




Background


Regulatory-associated protein of mTOR also known as raptor or KIAA1303 is an adapter protein that is encoded in humans by the RPTOR gene. RPTOR encodes part of a signaling pathway regulating cell growth which responds to nutrient and insulin levels. RPTOR is an evolutionarily conserved protein with multiple roles in the mTOR pathway. The adapter protein and mTOR kinase form a stoichiometric complex. The encoded protein also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. It upregulates S6 kinase, the downstream effector ribosomal protein, and it downregulates the mTOR kinase. RPTOR also has a positive role in maintaining cell size and mTOR protein expression. The association of mTOR and RPTOR is stabilized by nutrient deprivation and other conditions which suppress the mTOR pathway.




Images



Picture 1.png

Western blot analysis of Raptor (GB11590) at dilution of 1: 500





Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).


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