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Product Information
Description |
mTOR rabbit polyclonal antibody |
Protein full name |
Serine/threonine-protein kinase mTOR |
Synonyms |
FK506-binding protein 12-rapamycin complex-associated protein 1, Mammalian target of rapamycin, Rapamycin target protein 1, FRAP, FRAP1, FRAP2, RAFT1, RAPT1, mTOR |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Human mTOR |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
Cytoplasm, Nucleus |
Predicted MW. |
289 kDa |
Observed MW. |
289 kDa |
Uniprot ID |
P42345, Q9JLN9, P42346 |
Applications
Applications |
Species |
Dilution |
Positive Sample |
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
heart, liver, brain |
IHC/IF |
Human, Mouse, Rat |
1: 200-1: 600 |
brain, esophagus cancer |
Background
MTOR, also named as FRAP1, FRAP, FRAP2 and RAPT1, belongs to the PI3/PI4-kinase family. MTOR is a Ser/Thr protein kinase that functions as an ATP and amino acid sensor to balance nutrient availability and cell growth. MTOR is kinase subunit of both mTORC1 and mTORC2, which regulate cell growth and survival in response to nutrient and hormonal signals. MTOR has a calculated molecular mass of 289 kDa, and always can be detected at about 250 kDa due to some modifications.
Images
|
Western blot analysis of mTOR (GB111839) at dilution of 1: 500 |
|
Immunohistochemistry of paraffin embedded human esophagus cancer using mTOR (GB111839) at dilution of 1: 300 (200x lens) |
|
Immunohistochemistry of paraffin embedded mouse brain using mTOR (GB111839) at dilution of 1: 300 (200x lens) |
|
Immunohistochemistry of paraffin embedded rat brain using mTOR (GB111839) at dilution of 1: 300 (200x lens)
|
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).
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