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Anti -mTOR Rabbit pAb

价格: 在线咨询
货号:
KT012200
产品规格:
100 μL
Applications:
WB/IHC/IF
Species:
HMR/HMR
购买数量:
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产品详情 操作说明 注意事项

Product Information


Description

mTOR rabbit polyclonal antibody

Protein full name

Serine/threonine-protein kinase mTOR 

Synonyms

FK506-binding protein 12-rapamycin complex-associated protein 1, Mammalian target of rapamycin, Rapamycin target protein 1, FRAP, FRAP1, FRAP2, RAFT1, RAPT1, mTOR

Immunogen

KLH conjugated Synthetic peptide corresponding to Human mTOR

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm, Nucleus

Predicted MW.

289 kDa

Observed MW.

289 kDa

Uniprot ID

P42345, Q9JLN9, P42346




Applications


Applications

Species

Dilution

Positive Sample

WB

Human, Mouse, Rat

1: 500-1: 1000

heart, liver, brain

IHC/IF

Human, Mouse, Rat

1: 200-1: 600

brain, esophagus cancer




Background


MTOR, also named as FRAP1, FRAP, FRAP2 and RAPT1, belongs to the PI3/PI4-kinase family. MTOR is a Ser/Thr protein kinase that functions as an ATP and amino acid sensor to balance nutrient availability and cell growth. MTOR is kinase subunit of both mTORC1 and mTORC2, which regulate cell growth and survival in response to nutrient and hormonal signals. MTOR has a calculated molecular mass of 289 kDa, and always can be detected at about 250 kDa due to some modifications.




Images


Picture 1.png

Western blot analysis of mTOR (GB111839) at dilution of 1: 500

Picture 2.png

Immunohistochemistry of paraffin embedded human esophagus cancer using mTOR (GB111839) at dilution of 1: 300 (200x lens)

Picture 3.png

Immunohistochemistry of paraffin embedded mouse brain using mTOR (GB111839) at dilution of 1: 300 (200x lens)

Picture 4.png

Immunohistochemistry of paraffin embedded rat brain using mTOR (GB111839) at dilution of 1: 300 (200x lens)





Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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