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产品详情
操作说明
注意事项
Product Information
|
Description |
mTOR rabbit polyclonal |
|
Protein full name |
Serine/threonine-protein kinase mTOR |
|
Synonyms |
FK506-binding protein 12-rapamycin complex-associated protein 1, Mammalian target of rapamycin, Rapamycin target protein 1, FRAP, FRAP1, FRAP2, RAFT1, RAPT1, mTOR |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Human mTOR |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Cytoplasm, Nucleus |
|
Predicted MW. |
289 kDa |
|
Observed MW. |
289 kDa |
|
Uniprot ID |
P42345, Q9JLN9, P42346 |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Human, Mouse, Rat |
1: 400-1: 800 |
heart, liver, brain |
Background
MTOR, also named as FRAP1, FRAP, FRAP2 and RAPT1, belongs to the PI3/PI4-kinase family. MTOR is a Ser/Thr protein kinase that functions as an ATP and amino acid sensor to balance nutrient availability and cell growth. MTOR is kinase subunit of both mTORC1 and mTORC2, which regulate cell growth and survival in response to nutrient and hormonal signals. MTOR has a calculated molecular mass of 289 kDa, and always can be detected at about 250 kDa due to some modifications.
Images
|
|
Western blot analysis of mTOR (GB111840) at dilution of 1: 800 Lane 1: HEK293 cell lysate Lane 2: HepG2 cell lysate Lane 3: MCF7 cell lysate Lane 4: Mouse heart tissue lysate Lane 5: Mouse liver tissue lysate Lane 6: Mouse brain tissue lysate Lane 7: Rat heart tissue lysate Lane 8: Rat liver tissue lysate Lane 9: Rat brain tissue lysate |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室