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产品详情
操作说明
注意事项
Product Information
|
Description |
XIAP rabbit polyclonal antibody |
|
Protein full name |
E3 ubiquitin-protein ligase XIAP |
|
Synonyms |
Baculoviral IAP repeat-containing protein 4, IAP-like protein, API3, BIRC4, IAP3, XIAP, ILP, hILP, Inhibitor of apoptosis protein 3, IAP-3, hIAP3, X-linked IAP |
|
Immunogen |
Recombinant protein corresponding to Mouse XIAP |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
57 kDa |
|
Observed MW. |
57 kDa |
|
Uniprot ID |
P98170, Q60989 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Human, Mouse |
1: 500-1: 1000 |
MCF-7, HT-29, Jurkat, Raji, PC-12, HepG2 |
Background
XIAP, also named as API3, BIRC4 and IAP3, belongs to the IAP family. It has E3 ubiquitin-protein ligase activity. It mediates the proteasomal degradation of target proteins, such as caspase-3, SMAC or AIFM1. XIAP is an inhibitor of caspase-3, -7 and -9. It mediates activation of MAP3K7/TAK1, leading to the activation of NF-kappa-B. XIAP is an apoptotic suppressor. It is ubiquitinated and degraded by the proteasome in apoptotic cells.
Images
|
|
Western blot analysis of XIAP (GB111208) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室