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Anti -Bax Rabbit pAb

价格: 在线咨询
货号:
KT012178
产品规格:
100ul
Applications:
IHC/IF
Species:
H/M/R,H/M/R
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information


Description

Bax rabbit polyclonal antibody

Protein full name

Apoptosis regulator Bax

Synonyms

BCL2 Associated X Protein ,Bcl-2-Like Protein 4,BCL2L4,Bcl2-L-4

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Bax

Isotype

IgG

Purity

Affinity purification

Subcellular location

Mitochondrion membrane, Cytoplasm

Uniprot ID

Q07812,Q07813,Q63690



Applications


applications

species

dilution

Positive tissue

IHC

Human,Mouse,Rat

1:500-1:1000

Stomach cancer,

lung,colon

IF

Human,Mouse,Rat

1:500-1:1000

Stomach cancer,

lung,colon




Background


Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.




Images


Picture 1.png

Immunohistochemistry of paraffin embedded human breast cancer using Bax (GB11007-1) at dilution of 1:500 (400x lens)

Picture 2.png

Immunohistochemistry of paraffin embedded mouse small intestine using Bax (GB11007-1) at dilution of 1:500 (400x lens)

Picture 3.png

Immunohistochemistry of paraffin embedded rat pneumonia using Bax (GB11007-1) at dilution of 1:500 (400x lens)

Picture 4.png

Immunofluorescence of paraffin embedded human gastric cancer using Bax (GB11007-1) at dilution of 1:500 (400x lens)

Picture 5.png

Immunofluorescence of paraffin embedded human stomach using Bax (GB11007-1) at dilution of 1:500 (400x lens)

Picture 6.png

Immunofluorescence of paraffin embedded rat myocardial infarction using Bax (GB11007-1) at dilution of 1:500 (400x lens)

Picture 7.png

Immunofluorescence of paraffin embedded rat spleen using Bax (GB11007-1) at dilution of 1:500 (400x lens)




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).


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