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Product Information
Description |
Topoisomerase II alpha rabbit polyclonal antibody |
Protein full name |
DNA topoisomerase 2-alpha |
Synonyms |
DNA topoisomerase II, alpha isozyme, TOP2A, Top-2, Top2 |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse TOP2A |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
Cytoplasm, Nucleus |
Uniprot ID |
P11388, Q01320, P41516 |
Applications
Applications |
Species |
Dilution |
Positive Sample |
IHC/IF |
Human, Mouse, Rat |
1: 1500-1: 3000 |
brain, breast cancer, colon, placenta, testis, thymus |
Background
TOP2A, also named as TOP2, belongs to the type II topoisomerase family. Topoisomerase II makes double-strand breaks. TOP2 control the topological states of DNA by transient breakage and subsequent rejoining of DNA strands.
Images
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Immunohistochemistry of paraffin embedded human breast cancer using TOP2A (GB111293) at dilution of 1:1400 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse colon using TOP2A (GB111293) at dilution of 1:1400 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse placenta using TOP2A (GB111293) at dilution of 1:1400 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse testis using TOP2A (GB111293) at dilution of 1:1400 (400x lens) |
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Immunohistochemistry of paraffin embedded rat colon using TOP2A (GB111293) at dilution of 1:1400 (400x lens) |
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Immunohistochemistry of paraffin embedded rat placenta using TOP2A (GB111293) at dilution of 1:1400 (400x lens) |
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Immunofluorescence of paraffin embedded human colon using TOP2A (GB111293) at dilution of 1:1400 (400x lens) |
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Immunofluorescence of paraffin embedded mouse brain using TOP2A (GB111293) at dilution of 1:1400 (400x lens) |
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Immunofluorescence of paraffin embedded mouse testis using TOP2A (GB111293) at dilution of 1:1400 (400x lens) |
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Immunofluorescence of paraffin embedded rat thymus using TOP2A (GB111293) at dilution of 1:1400 (400x lens) |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).
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