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Product Information
Description |
KRT81 rabbit polyclonal antibody |
Protein full name |
Keratin, type II cuticular Hb1 |
Synonyms |
Keratin-81, K81, Type II hair keratin Hb1, Krt81, Krt2-19, ghHKb1, MLN137 |
Immunogen |
Recombinant protein corresponding to Mouse KRT81 |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
Cytoskeleton |
Uniprot ID |
Q14533, Q9ERE2 |
Applications
Applications |
Species |
Dilution |
Positive Sample |
IHC/IF |
Human, Mouse, Rat |
1: 400-1: 1200 |
skin, thymus |
Background
The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5.Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix.
Images
|
Immunofluorescence of paraffin embedded human skin using KRT81 (GB111745) at dilution of 1:650 (300x lens) |
|
Immunofluorescence of paraffin embedded mouse thymus using KRT81 (GB111745) at dilution of 1:650 (400x lens) |
Immunofluorescence of paraffin embedded rat thymus using KRT81 (GB111745) at dilution of 1:650 (400x lens) |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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