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Anti -Cytokeratin 6 Rabbit pAb

价格: 在线咨询
货号:
KT011910
产品规格:
100ul
Applications:
WB/IHC/IF
Species:
H/M,H/M/R,H/M/R
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information


Description

Cytokeratin 6 rabbit polyclonal

Protein full name

Keratin, type II cytoskeletal 6A

Synonyms

Cytokeratin-6A, CK-6A, Keratin-6-alpha, mK6-alpha, Keratin-6A, K6A, Krt6a, Ker2, Krt2-6, Krt2-6a, Krt6

Immunogen

Recombinant protein corresponding to Mouse Cytokeratin 6a

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm

Predicted MW.

59 kDa

Observed MW.

59 kDa

Uniprot ID

P02538P50446Q4FZU2




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse

1: 500-1: 1000

skin

IHC

Human, Mouse, Rat

1: 1000-1: 2000

tonsils, skin, stomach

IF

Human, Mouse, Rat

1: 1000-1: 3000

skin, stomach




Background


The protein encoded by this gene is a member of the keratin gene family. The Krt6 belongs to type II cytokeratins and consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin(KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. Mutations in these genes have been associated with pachyonychia congenita.




Images


Western blot analysis of CK6 (GB111247) at dilution of 1: 1000
Lane 1: A431 cell lysate
Lane 2: Mouse skin tissue lysate

Immunohistochemistry analysis of paraffin-embedded human tonsil using CK6 (GB111247) at dilution of 1: 1000

Immunohistochemistry analysis of paraffin-embedded mouse skin using CK6 (GB111247) at dilution of 1: 1000

image.png

Immunohistochemistry analysis of paraffin-embedded rat skin using CK6 (GB111247) at dilution of 1: 1000

Immunohistochemistry analysis of paraffin-embedded rat stomach using CK6 (GB111247) at dilution of 1: 1000

Immunofluorescent analysis of paraformaldehyde-fixed mouse skin using CK6 (GB111247) at dilution of 1: 1000

image.png

Immunofluorescent analysis of paraformaldehyde-fixed rat stomach using CK6 (GB111247) at dilution of 1: 1000




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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