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Product Information
Description |
Properdin/PFC rabbit polyclonal |
Protein full name |
Properdin |
Synonyms |
Complement factor P, Cfp, Pfc, BFD, Properdin P factor complement |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse Properdin |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
50 kDa |
Observed MW. |
53 kDa |
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Mouse, Rat |
1: 500-1: 1000 |
plasma |
Background
A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes.
Involvement in disease:Defects in CFP are the cause of properdin deficiency (PFD). PFD results in higher susceptibility to bacterial infections; especially to meningococcal infections. Three phenotypes have been reported: complete deficiency (type I), incomplete deficiency (type II), and dysfunction of properdin (type III).
Images
|
Western blot analysis of Properdin (GB112049) at dilution of 1: 1000 Lane 1: Mouse plasma tissue lysate Lane 2: Rat plasma tissue lysate |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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