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产品详情
操作说明
注意事项
Product Information
|
Description |
CD35 rabbit polyclonal |
|
Protein full name |
Complement receptor type 1 |
|
Synonyms |
C3b/C4b receptor, CD35, CR1, C3BR, C3 binding protein, C4BR , Knops blood group antigen |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Human CD35 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
224 kDa |
|
Observed MW. |
224 kDa |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Mouse, Rat |
1: 500-1: 1000 |
inflamed spleen, inflamed lung, inflamed kidney
|
|
IF |
Human, Rat | 1:650-1:1300 |
|
Background
This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus and sarcoidosis.
Images
|
|
Western blot analysis of CD35 at dilution of 1: 1000 Lane 1: Mouse inflamed spleen tissue lysate Lane 2: Mouse inflamed lung tissue lysate Lane 3: Mouse inflamed kidney tissue lysate Lane 4: Rat inflamed lung tissue lysate |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室