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Product Information
Description |
CD8 beta rabbit polyclonal |
Protein full name |
T-cell surface glycoprotein CD8 beta chain |
Synonyms |
CD8b, Lymphocyte antigen 3, T-cell membrane glycoprotein Ly-3, d8b1, Ly-3, Lyt-3, Lyt3 |
Immunogen |
Recombinant protein corresponding to Mouse CD8 beta |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
Membrane |
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
IF |
Human, Rat |
1: 500-1: 1000 |
lung cancer, colon, spleen, thymus |
Background
The CD8B antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.
Images
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Immunofluorescent analysis of paraformaldehyde-fixed human lung cancer using CD8 beta (GB111742) at dilution of 1: 500 |
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Immunofluorescent analysis of paraformaldehyde-fixed human colon using CD8 beta (GB111742) at dilution of 1: 500 |
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Immunofluorescent analysis of paraformaldehyde-fixed rat spleen using CD8 beta (GB111742) at dilution of 1: 500 |
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Immunofluorescent analysis of paraformaldehyde-fixed rat thymus using CD8 beta (GB111742) at dilution of 1: 500
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Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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