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Product Information
Description |
CD4 rabbit polyclonal |
Protein full name | T-cell surface glycoprotein CD4 |
Synonyms |
CD4, CD4mut, CD4 molecule |
Immunogen | Recombinant protein corresponding to Mouse CD4 |
Isotype | IgG |
Purity | Affinity purification |
Subcellular location |
Cell membrane |
Uniprot ID | P06332,P01730 |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
IHC |
Human, Rat |
1:2000-1:4000 |
tonsil |
IF |
Human, Rat |
1:200-1:400 |
tonsil |
Background
This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
Images
|
Immunohistochemistry analysis of paraffin-embedded human tonsil using CD4(GB11064-1) at dilution of 1:200 |
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Immunohistochemistry analysis of paraffin-embedded human tonsil using CD4(GB11064-1) at dilution of 1:200 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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