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Product Information
Description |
beta Actin rabbit polyclonal |
Protein full name |
Actin, cytoplasmic 1 |
Synonyms |
ACTB, BRWS1, PS1TP5BP1, Beta-actin, actin beta, Beta Cytoskeletal Actin |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse β-Actin |
Isotype |
IgG |
Predicted MW. |
42 kDa |
Observed MW. |
45 kDa |
Purity |
Affinity purification |
Uniprot ID |
P60709, P60710, P60711 |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Human, Mouse, Rat |
1:1000-1:2000 |
lung, kidney, brain |
Background
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.In vertebrates 3 main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cytoskeleton and as mediators of internal cell motility .
Images
|
Western blot analysis of β-Actin (GB11001) at dilution of 1: 2000 Lane 1: U251 cell lysate Lane 2: N2A cell lysate Lane 3: c6 cell lysate Lane 4: Mouse lung tissue lysate Lane 5: Mouse kidney tissue lysate Lane 6: Mouse brain tissue lysate Lane 7: Rat lung tissue lysate Lane 8: Rat kidney tissue lysate Lane 9: Rat brain tissue lysate
|
Storage
Storage |
Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer |
PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
Publications:
|
Title |
Journal |
Pubmed ID |
Application |
1 |
Inhibition of miR-331-3p and miR-9-5p ameliorates Alzheimer's disease by enhancing autophagy. |
Theranostics |
33500732 |
WB |
2 |
STK3 Suppresses Ovarian Cancer Progression by Activating NF-κB Signaling to Recruit CD8+ T-Cells. |
Journal of Immunology Research |
33062724 |
WB |
3 |
Circadian Rhythm Protein Bmal1 Modulates Cartilage Gene Expression in Temporomandibular Joint Osteoarthritis via the MAPK/ERK Pathway. |
Frontiers in Pharmacology |
33041790 |
WB |
4 |
Conductive Hydroxyethyl Cellulose/Soy Protein Isolate/Polyaniline Conduits for Enhancing Peripheral Nerve Regeneration via Electrical Stimulation. |
Frontiers in Bioengineering and Biotechnology |
32719783 |
WB |
5 |
Dual inhibition of PFKFB3 and VEGF normalizes tumor vasculature, reduces lactate production, and improves chemotherapy in glioblastoma: insights from protein expression profiling and MRI. |
Theranostics |
32641990 |
WB |
6 |
Effects of electrical stimulation on cell activity, cell cycle, cell apoptosis and βcatenin pathway in the injured dorsal root ganglion cell. |
Molecular Medicine Reports |
32323840 |
WB |
7 |
Prognostic values of immune scores and immune microenvironment-related genes for hepatocellular carcinoma. |
Aging (Albany NY) |
32213661 |
WB |
8 |
Chronic sleep fragmentation shares similar pathogenesis with neurodegenerative diseases: Endosome-autophagosome-lysosome pathway dysfunction and microglia-mediated neuroinflammation. |
CNS Neuroscience Therapeutics |
31549780 |
WB |
9 |
High-Fat Diet Aggravates Acute Pancreatitis via TLR4-Mediated Necroptosis and Inflammation in Rats. |
Oxidative Medicine and Cellular Longevity |
31998444 |
WB |
10 |
High-Fat Diet Aggravates the Intestinal Barrier Injury via TLR4-RIP3 Pathway in a Rat Model of Severe Acute Pancreatitis. |
Mediators of Inflammation |
31933540 |
WB |
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