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Product Information
Description |
S100A9 rabbit polyclonal |
Protein full name |
Protein S100-A9 |
Synonyms |
Calgranulin-B, Leukocyte L1 complex heavy chain, MRP-14, p14, S100 calcium-binding protein A9, S100a9, Cagb, Mrp14 |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse S100A9 |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
Cytoplasm, Cell membrane, Secreted |
Predicted MW. |
13 kDa |
Observed MW. |
13 kDa |
Uniprot ID |
P31725, P50116 |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Mouse, Rat |
1: 300-1: 800 |
spleen, lung |
IHC |
Mouse, Rat |
1: 1500-1: 3000 |
lung, liver, spleen, small intestine |
IF |
Mouse, Rat |
1: 750-1: 1500 |
lung, spleen |
Background
Calcium-binding protein. Has antimicrobial activity towards bacteria and fungi. Important for resistance to invasion by pathogenic bacteria. Up-regulates transcription of genes that are under the control of NF-kappa-B. Plays a role in the development of endotoxic shock in response to bacterial lipopolysaccharide (LPS). Promotes tubulin polymerization when unphosphorylated. Promotes phagocyte migration and infiltration of granulocytes at sites of wounding. Plays a role as a pro-inflammatory mediator in acute and chronic inflammation and up-regulates the release of IL8 and cell-surface expression of ICAM1. Extracellular calprotectin binds to target cells and promotes apoptosis. Antimicrobial and proapoptotic activity is inhibited by zinc ions.
Images
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Western blot analysis of S100A9 (GB111149) at dilution of 1: 800 |
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Immunohistochemistry analysis of paraffin-embedded mouse lung using S100A9 at dilution of 1: 1800 |
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Immunohistochemistry analysis of paraffin-embedded rat lung using S100A9 (GB111149) at dilution of 1: 1800 |
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Immunohistochemistry analysis of paraffin-embedded mouse liver using S100A9 (GB111149) at dilution of 1: 1800 |
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Immunohistochemistry analysis of paraffin-embedded rat liver using S100A9 (GB111149) at dilution of 1: 1800 |
|
Immunohistochemistry analysis of paraffin-embedded mouse spleen using S100A9 (GB111149) at dilution of 1: 1800 |
|
Immunohistochemistry analysis of paraffin-embedded rat spleen using S100A9 (GB111149) at dilution of 1: 1800 |
|
Immunohistochemistry analysis of paraffin-embedded rat small intestine using S100A9 (GB111149) at dilution of 1: 1800 |
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Immunofluorescent analysis of paraffin-embedded mouse lung using S100A9 (GB111149) at dilution of 1: 1000 |
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Immunofluorescent analysis of paraffin-embedded mouse spleen using S100A9 (GB111149) at dilution of 1: 1000 |
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Immunofluorescent analysis of paraffin-embedded rat spleen using S100A9 (GB111149) at dilution of 1: 1000 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
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