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产品详情
操作说明
注意事项
Product Information
|
Description |
CAMK2B rabbit polyclonal antibody |
|
Protein full name |
Calcium/calmodulin-dependent protein kinase type II subunit beta |
|
Synonyms |
CaM kinase II subunit beta, CaMK-II subunit beta, Camk2b, Camk2d |
|
Immunogen |
Recombinant protein corresponding to Mouse CAMK2B |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
60 kDa |
|
Observed MW. |
60 kDa |
|
Uniprot ID |
Q13554, P28652, P08413 |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Human, Mouse, Rat |
1: 300-1: 600 |
HeLa, SH-SY5Y, U-251MG, Neuro2A, PC-12 |
Background
CaMKII beta (Calcium/calmodulin-dependent protein kinase type II subunit beta ), also named as CAMK2B, CAM2 or CAMKB, belongs to the protein kinase super family, CAMK Ser/Thr protein kinase family and CaMK subfamily. It is a member of the NMDAR signaling complex in excitatory synapses, it may functions autonomously after Ca2+ calmodulin binding and autophosphorylation, and is involved in dendritic spine and synapse formation, neuronal plasticity and regulation of sarcoplasmic reticulum Ca2+ transport in skeletal muscle. In neurons, plays an essential structural role in the reorganization of the actin cytoskeleton during plasticity by binding and bundling actin filaments in a kinase-independent manner.
Images
|
|
Western blot analysis of Camk2b at dilution of 1: 300 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室