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产品详情
操作说明
注意事项
Product Information
|
Description |
OB Cadherin rabbit polyclonal antibody |
|
Protein full name |
Cadherin-11 |
|
Synonyms |
OSF-4, Cdh11, Cad-11, Osteoblast cadherin, OB-cadherin |
|
Immunogen |
Recombinant protein corresponding to Mouse OB Cadherin |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
88 kDa |
|
Observed MW. |
120 kDa |
|
Uniprot ID |
P55287, P55288 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
lung, uterus |
Background
This gene encodes a type II classical cadherin from the cadherin super family, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Cadherin-11 (OB-Cadherin) is a marker of the loosely connected and migratory cellular elements of the mesenchyme. Expression of this particular cadherin in osteoblastic cell lines, and its up regulation during differentiation, suggests a specific function in bone development and maintenance. Recently, Cadherin-11 mRNA and protein were found to be expressed in most invasive breast cancer cell lines tested but not in non-invasive cell lines, suggesting that Cadherin-11 may be a marker for aggressive, invasive tumor subsets.
Images
|
|
Western blot analysis of OB-Cadherin (GB111278) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室