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Anti -MAdCAM1 Rabbit pAb

价格: 在线咨询
货号:
KT011877
产品规格:
100 μL
Applications:
IHC/IF
Species:
HMR
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information


Description

MAdCAM1 rabbit polyclonal antibody

Protein full name

Mucosal addressin cell adhesion molecule 1

Synonyms

MAdCAM-1, mMAdCAM-1, Madcam1, Addressin mucosal, hMAdCAM 1, MACAM1, Mucosal vascular addressin cell adhesion molecule 1

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse MAdCAM1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cell Membrane

Uniprot ID

Q61826, O70540




Applications


Applications

Species

Dilution

Positive Sample

IHC/IF

Human, Mouse, Rat

1: 500-1: 3000

appendix, colon, lung+LPS, pancreas+LPS, pancreatic, small intestine




Background


MAdCAM-1 is an immunoglobulin (Ig) cell adhesion molecule family member. MAdCAM-1 is involved in lymphocyte homing to mucosal sites and is expressed on high endothelial venules (HEV) of both mesenteric lymph nodes and Peyer’s patches. It has also been found to be expressed on sinus-lining cells of the spleen. The integrin, alpha 4 beta 7, has been shown to function as the MAdCAM-1 receptor. The Ig domains of MAdCAM-1 have been found to be critical to alpha 4 beta 7 binding. The mucin domain has been shown to have activity in L-Selectin binding.




Images


Picture 1.png

Immunohistochemistry of paraffin embedded mouse pancreatic using MADCAM1 (GB111006) at dilution of 1:1700 (400x lens)

Picture 2.png Immunohistochemistry of paraffin embedded mouse small intestine using MADCAM1 (GB111006) at dilution of 1:1700 (400x lens)
Picture 3.png Immunohistochemistry of paraffin embedded mouse small intestine using MADCAM1 (GB111006) at dilution of 1:1800 (400x lens)
Picture 4.png Immunohistochemistry of paraffin embedded rat colon using MADCAM1 (GB111006) at dilution of 1:1800 (400x lens)
Picture 5.png Immunohistochemistry of paraffin embedded rat colon using MADCAM1 (GB111006) at dilution of 1:3400 (400x lens)
Picture 6.png Immunohistochemistry of paraffin embedded rat pancreas+LPS using MADCAM1 (GB111006) at dilution of 1:1800 (400x lens)
Picture 7.png Immunohistochemistry of paraffin embedded rat pancreas+LPS using MADCAM1 (GB111006) at dilution of 1:3400 (400x lens)
Picture 8.png Immunohistochemistry of paraffin embedded rat pancreatic using MADCAM1 (GB111006) at dilution of 1:1700 (400x lens)
Picture 9.png Immunohistochemistry of paraffin embedded rat pancreatic using MADCAM1 (GB111006) at dilution of 1:1800 (400x lens)
Picture 10.png Immunofluorescence of paraffin embedded human appendix using MADCAM1 (GB111006) at dilution of 1:1800 (400x lens)
Picture 11.png Immunofluorescence of paraffin embedded human colon using MADCAM1 (GB111006) at dilution of 1:1800 (400x lens)
Picture 12.png

Immunofluorescence of paraffin embedded human colon using MADCAM1 (GB111006) at dilution of 1:1800 (400x lens)

Picture 13.png

Immunofluorescence of paraffin embedded mouse lung+LPS using MADCAM1 (GB111006) at dilution of 1:1800 (400x lens)




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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