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产品详情
操作说明
注意事项
Product Information
|
Description |
OB Cadherin rabbit polyclonal antibody |
|
Protein full name |
Cadherin-11 |
|
Synonyms |
OSF-4, Osteoblast cadherin, OB-cadherin, Cdh11, CAD11, Cadherin 11 type 2 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse OB Cadherin |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
88 kDa |
|
Observed MW. |
120 kDa |
|
Uniprot ID |
P55287, P55288, F1MAH6 |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
brain, lung, testis |
Background
The cadherin super family comprises a large number of membrane glycoproteins with one or more cadherin repeats, which are involved in Ca2+ dependent cell-cell adhesion. Cadherin-11, also known as OB-cadherin, is a type II classical cadherin. Classical cadherins are type I transmembrane proteins with an N-terminal extracellular domain containing five tandem cadherin repeats and a C-terminal cytoplasmic domain with a characteristic sequence for binding to catenins. Type I cadherins differ from type II cadherins by the presence of the HAV tripeptide motif in the most N-terminal cadherin repeat. Classic cadherins mediate cell-cell adhesion preferentially via homotypic interactions and form adherens juctions that have beta -catenin and p120 (ctn) at the cytoplasmic side of the junction. Homotypic cadherin interactions also transduce outside-in and inside-out cell signals.
Images
|
Western blot analysis of OB-Cadherin (GB111008) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室