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Anti -ADRM1/ARM-1 Rabbit pAb
价格：
在线咨询
货号：
KT012243
产品规格：
100 μL
Applications：
IHC/IF
Species：
HMR
购买数量：
产品详情
操作说明
注意事项
Product Information
|
Description |
ADRM1 rabbit polyclonal antibody |
|
Protein full name |
Proteasomal ubiquitin receptor ADRM1 |
|
Synonyms |
110 kDa cell membrane glycoprotein, Gp110, Adhesion-regulating molecule 1, ARM-1, Rpn13 homolog, ADRM1, Gp110 |
|
Immunogen |
Recombinant protein corresponding to Mouse ADRM1 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Cytoplasm, Nucleus |
|
Uniprot ID |
Q16186, Q9JMB5 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
IHC/IF |
Human, Mouse, Rat |
1: 1000-1: 2000 |
brain, breast cancer, colon cancer, esophagus, lung |
Background
ADRM1 is a 407 amino acid protein that localizes to both the nucleus and the cytoplasm and is thought to be involved in protein recruitment and cell adhesion. An integral membrane protein, ADRM1 functions to recruit UCH-L5, a deubiquitinating enzyme, to the 26S proteasome, and once at the proteasome it promotes the activity of UCH-L5. Additionally, ADRM1 is thought to mediate lymphocyte adhesion in endothelial cells and may thus play a role in lymphocyte homing. ADRM1 expression is induced by IFN-g in some cancer cell lines and its expression is upregulated in other metastatic cells, suggesting a role in carcinogenesis.
Images
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Immunohistochemistry of paraffin embedded human breast cancer using ADRM1 (GB111263) at dilution of 1:1000 (400x lens) |
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Immunohistochemistry of paraffin embedded human colon cancer using ADRM1 (GB111263) at dilution of 1:1000 (400x lens) |
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Immunohistochemistry of paraffin embedded human esophagus using ADRM1 (GB111263) at dilution of 1:1000 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse brain using ADRM1 (GB111263) at dilution of 1:1000 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse lung using ADRM1 (GB111263) at dilution of 1:1000 (400x lens) |
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Immunohistochemistry of paraffin embedded rat brain using ADRM1 (GB111263) at dilution of 1:1000 (400x lens) |
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Immunohistochemistry of paraffin embedded rat lung using ADRM1 (GB111263) at dilution of 1:1000 (400x lens) |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室