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产品详情
操作说明
注意事项
Product Information
|
Description |
NDP rabbit polyclonal antibody |
|
Protein full name |
Norrin |
|
Synonyms |
Norrie disease protein homolog, Ndp, Ndph, FEVR, EVR2, X linked exudative vitreoretinopathy 2 protein |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse NDP |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
15 kDa |
|
Observed MW. |
15 kDa |
|
Uniprot ID |
P48744 |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Mouse, Rat |
1: 500-1: 1000 |
brain, testis, liver |
Background
NDP, also named as EVR2, ND and Norrin, is a secreted regulatory protein that remains tightly associated with the extracellular matrix. Mutations in the NDP gene are associated with the Norrie disease. Signaling induced by the protein NDP regulates vascular development of vertebrate retina and controls important blood vessels in the ear. It binds with high affinity to Frizzled 4, and Frizzled 4 knockout mice exhibit abnormal vascular development of the retina.
Images
|
Western blot analysis of Ndp (GB112642) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室