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Product Information
Description |
LGR5 rabbit polyclonal antibody |
Protein full name |
Leucine-rich repeat-containing G-protein coupled receptor 5 |
Synonyms |
G-protein coupled receptor 49, Orphan G-protein coupled receptor FEX, Lgr5, Gpr49, FEX, HG38 |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse LGR5 |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
100 kDa |
Observed MW. |
130 kDa |
Uniprot ID |
O75473, Q9Z1P4 |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
kidney |
Background
The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene.
Images
|
Western blot analysis of GPR49 (GB112018) at dilution of 1: 500 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).
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