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产品详情
操作说明
注意事项
Product Information
|
Description |
NF-κB p65 (phospho S536) rabbit polyclonal antibody |
|
Protein full name |
Transcription factor p65 |
|
Synonyms |
RELA, NFKB3, p65, RELA proto-oncogene, NF-kB subunit |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to human NF-κB p65 around the phosphorylation site of Serine 536 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
65 kDa |
|
Observed MW. |
65KDa |
|
Uniprot ID |
Q04206,Q04207 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Human, Mouse, Rat |
1: 600-1: 1000 |
lung, spleen, liver |
Background
NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity.
Images
|
|
Western blot analysis of P-NFkBp65 (GB11142-1) at dilution of 1: 600 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室