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Anti -Beclin 1 Rabbit pAb
价格：
在线咨询
货号：
KT012182
产品规格：
100 μL
Applications：
IHC/IF
Species：
H,M
购买数量：
产品详情
操作说明
注意事项
Product Information
|
Description |
Beclin1 rabbit polyclonal antibody |
|
Protein full name |
Beclin-1 |
|
Synonyms |
BECN1, ATG6, NVPS30, beclin1, beclin-1, GT197 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse Beclin1 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Cytoplasm, Nucleus |
|
Uniprot ID |
Q14457 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
IHC/IF |
Human, Mouse |
1: 500-1: 4000 |
kidney |
Background
Plays a central role in autophagy . Acts as core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 . Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex forms.
Images
|
|
Immunofluorescence of paraffin embedded mouse kidney using Beclin1 (GB11228) at dilution of 1:2200 (400x lens) |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室