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Anti -Beclin 1 Rabbit pAb

价格: 在线咨询
货号:
KT012182
产品规格:
100 μL
Applications:
IHC/IF
Species:
H,M
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information


Description

Beclin1 rabbit polyclonal  antibody

Protein full name

Beclin-1

Synonyms

BECN1, ATG6, NVPS30, beclin1, beclin-1, GT197

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Beclin1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm, Nucleus

Uniprot ID

Q14457



Applications


Applications

Species

Dilution

Positive Sample

IHC/IF

Human, Mouse

1: 500-1: 4000

kidney



Background



Plays a central role in autophagy . Acts as core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 . Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex forms.




Images



Picture 1.png

Immunofluorescence of paraffin embedded mouse kidney using Beclin1 (GB11228) at dilution of 1:2200 (400x lens)




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).



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