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产品详情
操作说明
注意事项
Product Information
|
Description |
KMT3C/SMYD2 rabbit polyclonal antibody |
|
Protein full name |
N-lysine methyltransferase SMYD2 |
|
Synonyms |
Histone methyltransferase SMYD2, SET and MYND domain-containing protein 2, Smyd2, Lysine N-methyltransferase 3C, MGC119305, N lysine methyltransferase SMYD2 |
|
Immunogen |
Recombinant protein corresponding to Mouse SMYD2 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Nucleus, Cytoplasm |
|
Uniprot ID |
Q8R5A0, Q7M6Z3 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
IHC/IF |
Mouse, Rat |
1: 1000-1: 4000 |
Bone fibroids, brain, heart, Skeletal muscle |
Background
Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Has also methyltransferase activity toward non-histone proteins such as p53/TP53 and RB1. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53.
Images
|
|
Immunohistochemistry of paraffin embedded mouse heart using SMYD2 (GB111583) at dilution of 1:2000 (400x lens) |
|
|
Immunofluorescence of paraffin embedded mouse brain using SMYD2 (GB111583) at dilution of 1:2000 (400x lens) |
|
|
Immunofluorescence of paraffin embedded mouse Skeletal muscle using SMYD2 (GB111583) at dilution of 1:1000 (400x lens) |
|
|
Immunofluorescence of paraffin embedded rat Bone fibroids using SMYD2 (GB111583) at dilution of 1:2000 (400x lens) |
|
|
Immunofluorescence of paraffin embedded rat heart using SMYD2 (GB111583) at dilution of 1:2000 (400x lens) |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室