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Anti -KMT1B / SUV39H2 Rabbit pAb

价格: 在线咨询
货号:
KT012137
产品规格:
100 μL
Applications:
IHC/IF
Species:
H,M,R
购买数量:
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产品详情 操作说明 注意事项

Product Information


Description

SUV39H2 rabbit polyclonal antibody

Protein full name

Histone-lysine N-methyltransferase SUV39H2

Synonyms

Histone H3-K9 methyltransferase 2, KMT1B, H3-K9-HMTase 2, Lysine N-methyltransferase 1B, Suppressor of variegation 3-9 homolog 2, Su(var)3-9 homolog 2, SUV39H2

Immunogen

Recombinant protein corresponding to Mouse SUV39H2

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus

Uniprot ID

Q9H5I1




Applications


Applications

Species

Dilution

Positive Sample

IHC/IF

Human, Mouse, Rat

1: 500-1: 4000

breast cancer, hippocampus, testis




Background


Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 'Lys-9' trimethylation is also required to direct DNA methylation at pericentric repeats.




Images


Picture 1.png Immunohistochemistry of paraffin embedded human breast cancer using Suv39h2 (GB111054) at dilution of 1:2000 (400x lens)
Picture 2.png Immunofluorescence of paraffin embedded human breast cancer using Suv39h2 (GB111054) at dilution of 1:2000 (400x lens)
Picture 3.png Immunofluorescence of paraffin embedded mouse hippocampus using Suv39h2 (GB111054) at dilution of 1:2000 (400x lens)

Picture 4.png

Immunofluorescence of paraffin embedded rat testis using Suv39h2 (GB111054) at dilution of 1:2000 (400x lens)




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).


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