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Anti -NFkB p100/NFKB2 Rabbit pAb
价格：
在线咨询
货号：
KT012141
产品规格：
100ul
Applications：
WB
Species：
H/M/R
购买数量：
产品详情
操作说明
注意事项
Product Information
|
Description |
NFKB2 rabbit polyclonal antibody |
|
Protein full name |
Nuclear factor NF-kappa-B p100 subunit |
|
Synonyms |
DNA-binding factor KBF2, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, Nuclear factor NF-kappa-B p52 subunit, Nfkb2, Lyt10, H2TF1 |
|
Immunogen |
Recombinant protein corresponding to Human NFKB2 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
97 kDa |
|
Observed MW. |
110 kDa |
|
Uniprot ID |
Q00653, Q9WTK5, Q5U2Z4 |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
lung, spleen, stomach |
Background
NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. NFKB2 appears to have dual functions such as cytoplasmic retention of attached NF-kappa-B proteins by p100 and generation of p52 by a cotranslational processing. The proteasome-mediated process ensures the production of both p52 and p100 and preserves their independent function. P52 binds to the kappa-B consensus sequence 5'-GGRNNYYCC-3', located in the enhancer region of genes involved in immune response and acute phase reactions.
Images
|
|
Western blot analysis of H2TF1 (GB111053) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室